Oxidative Stress and Inflammatory Markers in Abdominal Aortic Aneurysm
نویسندگان
چکیده
منابع مشابه
Inflammatory abdominal aortic aneurysm.
A73-year-old woman who had been losing weight progressively (26 kg) over a period of 6 months came to our hospital after experiencing growing abdominal pain for 2 weeks. A CT of the abdomen revealed a 6-cm infrarenal abdominal aortic aneurysm surrounded by a contrast-enhancing mantel (Figure 1). Her C-reactive protein value was 4.3 mg/dL. Other laboratory tests revealed no specific findings. Th...
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OBJECTIVE Oxidative stress plays a critical role in the development of abdominal aortic aneurysm (AAA). Intermedin (IMD) is a regulator of oxidative stress. Here, we investigated whether IMD reduces AAA by inhibiting oxidative stress. APPROACH AND RESULTS In angiotensin II-induced ApoE-/- mouse and CaCl2-induced C57BL/6J mouse model of AAA, IMD1-53 significantly reduced the incidence of AAA a...
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Dear Editor,Abdominal aortic aneurysm is often asymptomatic, less recognized, and causes considerable mortality and morbidity, if missed. The incidence varies from country to country and the occurrence is influenced by modifiable (smoking, coronary heart disease, hypertension, dyslipidemia, and prolonged steroid therapy) and non-modifiable risk factors (increasing age, male gender, and positive...
متن کاملAortic iron overload with oxidative stress and inflammation in human and murine abdominal aortic aneurysm.
OBJECTIVE Although iron is an essential element for maintaining physiological function, excess iron leads to tissue damage caused by oxidative stress and inflammation. Oxidative stress and inflammation play critical roles for the development of abdominal aortic aneurysm (AAA). However, it has not been investigated whether iron plays a role in AAA formation through oxidative stress and inflammat...
متن کاملSurrogate Markers of Abdominal Aortic Aneurysm Progression.
The natural course of many abdominal aortic aneurysms (AAA) is to gradually expand and eventually rupture and monitoring the disease progression is essential to their management. In this publication, we review surrogate markers of AAA progression. AAA diameter remains the most widely used and important marker of AAA growth. Standardized reporting of reproducible methods of measuring AAA diamete...
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ژورنال
عنوان ژورنال: Antioxidants
سال: 2021
ISSN: 2076-3921
DOI: 10.3390/antiox10040602